|
|
linolenic_acid + ATP + CoA <=> linolenoyl-CoA + diphosphate + AMP
|
1.13.12.7
firefly luciferase
6.2.1.2
medium-chain acyl-CoA ligase
6.2.1.3
long-chain-fatty-acid---CoA ligase
|
–
–
–
|
|
BRENDA:
BS286
MetaCyc:
LINOLENOYL-RXN
|
|
|
|
(3R,8Z,11Z,14Z,17Z)-3-hydroxyicosatetraenoyl-CoA <=> (2E,8Z,11Z,14Z,17Z)-icosapentaenoyl-CoA + H2O
|
4.2.1.134
very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase
|
–
|
|
MetaCyc:
RXN-16021
|
|
|
|
linolenoyl-CoA + O2 + ferricytochrome_b5 + H+ <=> stearidonoyl-CoA + H2O + ferricytochrome_b5
|
1.14.19.3
acyl-CoA 6-desaturase
|
–
|
|
BRENDA:
BR51360
KEGG:
R07933
MetaCyc:
RXN-13426
|
|
|
|
(8Z,11Z,14Z,17Z)-icosa-8,11,14,17-tetraenoyl-CoA + O2 + ferricytochrome_b5 + H+ <=> eicosapentaenoyl-CoA + H2O + ferricytochrome_b5
|
1.14.19.44
acyl-CoA (8-3)-desaturase
|
–
|
|
BRENDA:
BR51509
KEGG:
R11060
MetaCyc:
RXN-13429
|
|
|
|
(8Z,11Z,14Z,17Z)-3-oxoicosatetraenoyl-CoA + NADPH + H+ <=> (3R,8Z,11Z,14Z,17Z)-3-hydroxyicosatetraenoyl-CoA + NADP+
|
1.1.1.330
very-long-chain 3-oxoacyl-CoA reductase
|
–
|
|
MetaCyc:
RXN-16020
|
|
|
|
malonyl-CoA + stearidonoyl-CoA + H+ <=> (8Z,11Z,14Z,17Z)-3-oxoicosatetraenoyl-CoA + CoA + CO2
|
2.3.1
|
–
|
|
MetaCyc:
RXN-16019
|
|
|
|
(2E,8Z,11Z,14Z,17Z)-icosapentaenoyl-CoA + reduced_acceptor <=> (8Z,11Z,14Z,17Z)-icosa-8,11,14,17-tetraenoyl-CoA + acceptor
|
1.3.1.93
very-long-chain enoyl-CoA reductase
|
–
|
|
MetaCyc:
RXN-16022
|
|